My Best Isaac Run Yet!!!
1:06:33
My Best Isaac Run Yet!!!
4 views2 months ago
YouTubewoonkey
Day 8 🠮 0 to 100% TBOI new save file
4:08:42
Day 8 🠮 0 to 100% TBOI new save file
512 views1 month ago
YouTubeQuinnjamin
Daily Isaac Run!
1:57:43
Daily Isaac Run!
31 views2 months ago
YouTubeXaiter
September 24 2025 Binding of Isaac Daily Run
30:46
September 24 2025 Binding of Isaac Daily Run
707 views5 months ago
YouTubetaelia
BEST ISAAC RUNS YOU'LL EVER SEE
3:30:11
BEST ISAAC RUNS YOU'LL EVER SEE
93 views2 months ago
YouTubeicee_adam
Road to Victory! Isaac Live Runs, Unlocks & Chaos! 4/5 Daily Run
1:32:58
Road to Victory! Isaac Live Runs, Unlocks & Chaos! 4/5 Daily Run
21 views3 months ago
YouTubeSlickyyNicky
HOW TO DESTROY A PERFECT RUN
5:00
HOW TO DESTROY A PERFECT RUN
5 views2 months ago
YouTubeAyça Güneş
1:02
This Item Carried the Run...
6.8K views2 months ago
YouTubeBrofessorSky
46:25
Wow, extremely good Isaac run.
1 views1 month ago
YouTubeAdam Kryczek
0:18
LET'S SOLVE RUNS IN #thebindingofisaac #kayhosyt
426.6K views1 month ago
YouTubeKayhos
1:00:16
Road to Victory! Isaac Live Runs, Unlocks & Chaos! 4/5 Daily Run p…
1 views3 months ago
YouTubeSlickyyNicky
1:47:55
Best Isaac Run There Ever WAS!!!!
1 month ago
YouTubeDKDante420
0:05
Easiest Isaac Run Guide for Beginners
2.4K views1 month ago
TikToktrellodon_x
0:15
Exploring The Binding of Isaac Game Mechanics
47.6K views4 months ago
TikTokod.moon
2:53:31
🔴 ISAAC SPEEDRUNS
1.9K views2 months ago
Twitch
Tutorial/Introduction to the Binding of Isaac (ft God Awful Run) | Bindi…
57.7K viewsMar 31, 2021
YouTubeMr Samuel Streamer
38:24
UNLOCKING THE FORGOTTEN! (Binding Of Isaac)
1.8M viewsFeb 14, 2019
YouTubeYuB
2:48
Unlocking D20 | The binding of Isaac: Repentance
27.1K viewsJul 6, 2021
YouTubeAsl1k lol
31:08
This Is What A 19 Hour Isaac Run Looks Like...
719.3K viewsMay 26, 2021
YouTubeDan Gheesling
11:04
How to Create CUSTOM CHALLENGES - The Binding of Isa…
30.5K viewsMay 8, 2021
YouTubeIsaacGuru
4:31:19
Ranking Every Item In The Binding Of Isaac
1.1M viewsFeb 10, 2021
YouTubeNorthernlion
7:56
The Binding Of Isaac: ALL 13 ENDINGS + INTRO, EPILOGUE, A…
3.6M viewsJun 25, 2012
YouTubeShadowRekiga
2:33
The Binding of Isaac - Unlockable Boss: It Lives
200.2K viewsOct 21, 2011
YouTubeHeironymo
12:50
HOW TO GIVE ITEMS! :: Binding of Isaac: Debug Console Tutorials :: 1
282.3K viewsFeb 24, 2018
YouTubeOlexa
1:03:01
The Binding of Isaac: Afterbirth - Gameplay Walkthrough Part 1 - Is…
477K viewsNov 1, 2015
YouTubeZackScottGames
15:07
The Binding Of Isaac Until Repentance FULL STORY EXPLAI…
526.9K viewsApr 2, 2021
YouTubeGamerSault
1:11:12
Beginner's Guide to | The Binding of Isaac: Rebirth | Part 1 of 2
235.9K viewsJun 4, 2015
YouTubeAzure Raiden
31:18
The Binding of Isaac 100% Walkthrough [HD] [#01] - The first …
200.8K viewsMar 11, 2012
YouTubeTheKuskus23
5:05
How to Isaac Sprites [Tutorial and Tips etc.]
235.6K viewsSep 29, 2016
YouTubeLeatherIceCream
30:05
The Binding of Isaac: Rebirth - Gameplay Walkthrough Part 11 - B…
185.3K viewsNov 13, 2014
YouTubeZackScottGames
See more videos
Static thumbnail place holder