A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

Abstract: Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological features.

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Pulmonary arterial hypertension (PAH) involves progressive cellular and molecular change within the pulmonary vasculature, leading to increased vascular resistance. Current therapies targeting nitric ...

Abstract: Spatial transcriptomics (ST) enables the joint profiling of gene expression and spatial localization, offering new insights into tissue microenvironments and biological processes. However, ...

Advancements in spatial perturbation transcriptomics (SPT) have revolutionized our understanding of cellular behavior in native tissue contexts by integrating spatial and perturbation data. However, ...

COURTESY OF ELANA FERTIG Wu reflects on Fertig's research studying cancer using computational approaches including spatial biology. “The [pancreatic] tumor has a very dense, immunosuppressive ...