Scientists have developed a network of mechanical motors that mimic the molecular machinery underpinning human muscle ...

A new study from researchers at the University of Virginia has revealed an important discovery that may help scientists develop improved treatments for high blood pressure in the future. The research ...

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization ...

High blood pressure, also known as hypertension, is one of the most widespread health problems in the world. In the United States alone, more than 116 million adults are affected by this condition.

Atherosclerosis is a complex, chronic inflammatory disease, traditionally considered a lipid-driven and immune-mediated disorder whose pathogenesis involves the interplay of multiple cellular ...

Introduction: Coronary artery disease (CAD) remains the leading cause of global mortality, with genetic factors conferring about 50% of disease susceptibility. GWAS have identified numerous genomic ...

Senescent vascular smooth muscle cells (VSMCs) accumulate during atherosclerosis and produce the senescence-associated secretory phenotype (SASP), which disrupts the extracellular matrix and increases ...

This fundamental research conducted a molecular comparison between smooth muscle cells and adjacent fibroblast cells within lung blood vessels affected by pulmonary arterial hypertension. The study ...