Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, 30 South 2000 East, Room 201 Skaggs Hall, Salt Lake City, Utah 84112, United States ...
Previous studies have reported the presence of interferon‐responsive microglia in the brain after central nervous system injury. However, their roles and the underlying mechanisms in neurological ...
Objectives Eosinophilic bronchiectasis is defined by a blood eosinophil count (BEC) ≥300 cells/µL, but blood eosinophils imperfectly reflect airway eosinophilic inflammation. Here, we investigated the ...
Blockade of IL1RAP (interleukin 1 receptor associated protein) was recently shown to reduce atherosclerosis in mice, but the effect on human vascular cells is largely unknown. Targeting the IL1RAP ...
Introduction Biannual (ie, every 6 months) mass drug administration of azithromycin has reduced childhood mortality in Niger, but its effects on specific respiratory pathogens are not fully elucidated ...
aDepartment of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia bSchool of Biological Sciences, Monash University, Clayton ...
α-Synuclein aggregation is a key pathological feature of Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, diseases for which we have no diagnostics nor disease-modifying ...
This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...
Platelet-derived growth factor-D (PDGF-D) is highly expressed in immune cells. However, the potential role of PDGF-D in immune system remains thus far unclear. Here, we reveal a novel function of PDGF ...
Understanding how mechanical signals influence fibroblast behavior is critical for understanding wound healing and fibrotic diseases. This study demonstrates that isometric stretching of tissues can ...