Scientists from UCL and Great Ormond Street Hospital have created the first lab grown oesophagus - the food pipe - shown to safely replace a full section of the organ and restore normal function, ...

Scientists from Great Ormond Street Hospital (GOSH) and University College London (UCL) have created the first lab‑grown esophagus—the food pipe—shown to safely replace a full section of the organ and ...

Scientists at MIT have discovered that a little-known protein called intelectin-2 plays a powerful double role in defending the gut. The protein strengthens the mucus layer that lines the ...

To most people, calorie absorption is the North Star of nutrition: a rigid quantity assigned to each and every food that never wavers or changes. Two individuals who eat the exact same thing in the ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Novo Nordisk has multiple weight-loss drugs in various stages of development and approval, according to its R&D pipeline. These include, among others, monlunabant (phase 2); oral and subcutaneous ...

For more than a century, the human appendix has been written off as a biological relic, a shrunken leftover from plant-eating ancestors that serves no real purpose. That view is now outdated. A ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

The appendix has independently evolved at least 32 times across 361 mammalian species. What makes it an evolutionary darling ...

What began as an unexpected observation and “side effect” of some medications converged with decades of addiction neuroscience: GLP-1 receptor agonist medications like Ozempic apparently reduce ...

Intestine-Mimicking Cell Model Accurately Predicts Drug Toxicity KRIBBs hIEC model detects gastrointestinal toxicity with 94% accuracy, offering early prediction of drug side effects ...

Despite clinical and scientific advancements, heart failure is the major cause of morbidity and mortality worldwide. Both mitochondrial dysfunction and inflammation contribute to the development and ...