Testosterone has been proposed to influence economic preferences such as risk taking, fairness, altruism, and competitiveness, with support from correlational studies and small-sample randomized ...

Olaparib as Treatment Versus Nonplatinum Chemotherapy in Patients With Platinum-Sensitive Relapsed Ovarian Cancer: Phase III SOLO3 Study Final Overall Survival Results We conducted a prospective ...

The Breakthrough Devices Program of the US Food and Drug Administration has accelerated the development and evaluation of medical devices for patients with heart failure. One such device is the ...

1 Department of Epidemiology and Biostatistics, University of California, San Francisco, 550 16th Street, San Francisco, CA, USA 2 Department of Psychiatry, University of California, San Francisco, CA ...

In a world of technological advancements, electronic devices and services seem to be a promising way to increase patients’ engagement in treatment and to help manage their symptoms. Here, we ...

Systematic pelvic and paraaortic lymphadenectomy has been widely used in the surgical treatment of patients with advanced ovarian cancer, although supporting evidence from randomized clinical trials ...

The well-recognized limitations of traditional randomized, controlled trials (RCTs), including their cost, the nature of the patients and providers included in them, and even the types of ...

We have already seen that varying two factors simultaneously provides an effective experimental design for exploring the main (average) effects and interactions of the factors 1. However, in practice, ...

Objectives National dietary guidelines were introduced in 1977 and 1983, by the US and UK governments, respectively, with the ambition of reducing coronary heart disease (CHD) by reducing fat intake.

The stepped wedge cluster randomised trial is a novel research study design that is increasingly being used in the evaluation of service delivery type interventions. The design involves random and ...

If you are working through this example on your computer, you might find a different run order in your output. This is due to the difference in the seed value of the random number generator. You can ...