T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

Mitochondrial calcium signalling plays a fundamental role in cellular homeostasis by modulating energy production and activating key metabolic enzymes. Calcium ions (Ca2+) are dynamically exchanged ...

As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and more restricted, leading ...

A lipid hidden within cells called phosphatidylserine reveals how the body initiates the removal of threats and cellular debris.

Researchers have identified a specific hormone produced by pancreatic beta cells as a direct driver of obesity-linked ...

Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism.

Photoreceptors are specialized cells in the eye that convert light energy into neural signals. Several diseases that cause irreversible vision loss, including age-related macular degeneration, ...