The first cell rejuvenation therapy is set to enter clinics, testing if aging cells can be reset to a younger, healthier ...

The powerful gene-editing technique CRISPR–Cas9 might offer a way to make safer, more effective cancer-fighting immune cells ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an ...

Cancer immunotherapy has transformed the treatment landscape for multiple malignancies; however, its clinical efficacy remains limited in many tumors due to ...

The researchers say that, to their knowledge, this is the first demonstration of programmable, site-specific integration of a large DNA payload into T cells in vivo.

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of the body, shipped to a specialized facility, genetically reprogrammed, ...

Japan’s health ministry has endorsed two stem-cell therapies derived from induced pluripotent stem (iPS) cells, making them the first treatments of their kind to clear a national regulatory body ...

The life science group Sartorius is launching an integrated system for the production and quality control (QC) of autologous cell therapies.

BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...