The powerful gene-editing technique CRISPR–Cas9 might offer a way to make safer, more effective cancer-fighting immune cells ...

A well-fitted ‘disguise’ allows transplanted mitochondria to slip into cells whose own mitochondria are defective, scientists reported 18 March in Cell 1. Administration of these cloaked mitochondria ...

Cancer immunotherapy has transformed the treatment landscape for multiple malignancies; however, its clinical efficacy remains limited in many tumors due to ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an ...

The researchers say that, to their knowledge, this is the first demonstration of programmable, site-specific integration of a large DNA payload into T cells in vivo.

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of the body, shipped to a specialized facility, genetically reprogrammed, ...

Japan’s health ministry has endorsed two stem-cell therapies derived from induced pluripotent stem (iPS) cells, making them the first treatments of their kind to clear a national regulatory body ...

The life science group Sartorius is launching an integrated system for the production and quality control (QC) of autologous cell therapies.