Immunometabolism has profoundly elucidated the central role of metabolism in regulating immune responses. Metabolism not only serves as the foundation for ...

An international research team from Bielefeld University and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP ...

Researchers at UC San Francisco have now developed a way to reprogram these cancer-fighting cells directly inside the body. This new method could remove the need for external manufacturing, ...

Until recently, the root cause of cachexia was identified as the inflammatory mediators produced either by the tumour itself ...

A breakthrough in CAR-T therapy may allow cancer treatment with a single injection, cutting costs and making care more available.

Digestive tract tumors are malignant diseases characterized by high aggressiveness, heterogeneity and metabolic abnormalities ...

To test whether AT2‑derived lipids are required for metastasis, the researchers selectively deleted Fasn in AT2 cells.

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of ...

Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a ...

Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed.For years, mitochondrial dysfunction has been recognized ...