E. coli RecBCD is a DNA helicase with two ATPase motors (RecB, a 3′→5′ translocase, and RecD, a 5′→3′ translocase) that function in repair of double-stranded DNA breaks. The RecBC heterodimer, with ...
In this issue, Wu et al. show that the RecBC helicase, which is involved in repairing double-strand DNA breaks, uses one ATPase motor to drive two translocases along opposite strands of DNA—much as an ...
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