Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and biomarker discovery in proteomics.

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

LA JOLLA, CA—Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, ...

Built on groundbreaking research from Israel ’s Weizmann Institute of Science, Promise Bio developed the first cloud-based platform for broad epiproteomics, helping researchers uncover disease ...

An AI model that reveals how protein modifications link genetic mutations to disease has been developed. Researchers at Baylor College of Medicine (TX, USA) have developed an AI model that reveals how ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene ...