Astrocytes reveal fragile X pathway tied to seizures and synapse problems

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite the ...
Mirage News

Astrocytes' Role in Fragile X Syndrome Unveiled

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite ...
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25 legal loopholes that defy common sense: uncover bizarre l

Uncover 25 legal loopholes that defy common sense. From police deception to surprising rights, explore bizarre laws and how ...
eLife

Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling

Using single-nucleus RNA sequencing, the authors map transcriptional changes in the rat ventral tegmental area following chronic inflammatory pain and acute morphine exposure. Notably, their ...
eLife

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...
Thorax

Sex-based differences in effectiveness of immune checkpoint inhibitors in the treatment of advanced non-small-cell lung cancer: systematic review and meta-anal…

Background Sex-based differences in immune response are well established, but whether men and women derive comparable benefit ...