The study will assess the tolerability, safety, maximum tolerated dose, and the recommended Phase II dose of PLT012.

Scientists at City of Hope and the Broad Institute and Keio University have discovered how specific gut bacteria work ...

New research shows how cancer cells use a vitamin B7-dependent pathway to survive in the absence of glutamine, revealing ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Tumor metabolomics is an emerging field focused on understanding the metabolic alterations that occur in tumor cells and their surrounding microenvironment. These changes are essential to support the ...

Scientists at City of Hope, the Broad Institute and Keio University have discovered how specific gut bacteria work together with diet to flip a metabolic switch — transforming energy‑storing white fat ...

A new study reports that GLP-1 semaglutide medications may help reverse the effects of osteoarthritis in the joints by ...

A new review outlines design principles and applications of synthetic membraneless organelles built through liquid-liquid phase separation for use in biotechnology.

Researchers identified invasive early disseminated cancer cells and immunosuppressive macrophage signaling that promote ...

The mechanism of action of mRNA vaccines goes far beyond harnessing host cellular machinery to produce antigenic proteins to spur immunity, write Nicolas Hulscher, M.P.H., Peter A. McCullough, M.D., M ...