The three-dimensional structure adopted by biological macromolecules largely determines their role in different cellular processes. Several different imaging techniques ranging from X-ray ...

Structural biology studies the 3D-dimensional structure of biological macromolecules, such as proteins and nucleic acids, as a tool to decipher their function and mechanisms of action. You may be ...

Lysosomes are dynamic organelles that receive membrane traffic input from the secretory, endocytic, autophagic and phagocytic pathways. They can also fuse with the plasma membrane. Live-cell imaging ...

Endocytosis, a fundamental process that cells use to take in macromolecules, functions a lot like an airlock on a spaceship -- but squishier, says a researcher. Researchers have studied how cells ...

In this special issue of Nature Structural Biology, we highlight the development of techniques to study molecular movements, the applications of those techniques and their impact on future directions ...