AlidaBio Introduces the EpiPlex™ Duo-Mod™ Service for Concurrent m6A and Inosine Mapping with Integrated RNA Expression Profiling

AlidaBio today announced the launch of the EpiPlex™ Duo-Mod™ Service, a turnkey offering that maps and quantifies m6A and ...
National Academies of Sciences%2c Engineering%2c and Medicine

Toward Sequencing and Mapping of RNA Modifications

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...
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Researchers produce first-ever toolkit for RNA sequencing analysis using a ‘pantranscriptome’

Diagram of the haplotype-aware transcriptome analysis pipeline. Analyzing a person’s gene expression requires mapping their RNA landscape to a standard reference to gain insight into the degree to ...
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Spatial RNA Medicine: The Next Frontier in Precision Therapeutics

Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...
Fred Hutch

Circling back to RNA sequencing data to map recursive splice sites

The human genome is just over 6 feet 8 inches long, which is 2 inches taller than the average NBA basketball player and in total, a lot of nucleotides! But what if the amount of sequence diversity ...
GEN

Beyond the Map: Capturing Abundance and Location of RNA Modifications from Ultra-Low Inputs

Once considered passive messengers of genetic information, RNA molecules are now understood to play an active and dynamic role in gene regulation, modulated by a rich layer of chemical modifications ...
News-Medical.Net on MSN

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell ...

AlidaBio Introduces the EpiPlex(TM) Duo-Mod(TM) Service for Concurrent m6A and Inosine Mapping with Integrated RNA Expression Profiling

RNA modifications are increasingly recognized as clinically relevant biomarkers, revealing immune dysregulation in autoimmune disease, early oncogenic signaling, and RNA misprocessing in ...
Science Daily

Researchers produce toolkit for RNA sequencing analysis using a 'pantranscriptome'

Researchers introduce a method for analyzing RNA sequencing data genome-wide using a 'pantranscriptome,' which combines a transcriptome and a pangenome, creating a richer reference that can address ...