The cerebral cortex, the brain’s outermost region responsible for higher cognitive functions, depends on a highly ordered, ...

Researchers discover that the RNA surveillance system NMD and the protein UPF2 are essential for guiding neuronal migration and forming the brain's layered cortex.

New research shows that physical pressure from brain tumors or injuries triggers a "self-destruction" program in neurons, leading to irreversible brain damage.

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

The cerebral cortex, the brain's outermost region responsible for higher cognitive functions, depends on a highly ordered ...

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord. This intricate communication network is built of billions of neurons connected by synapses ...

The ability to measure the connectivity of each neuron in a neural circuit has established large maps of neuronal pathways—the connectome. But the extent to which those connectivity measurements alone ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

Brain tumors do not just invade healthy tissue. They also physically squeeze it, and that mechanical compression may be enough to trigger neuron death in the surrounding brain. Two peer-reviewed ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the fatty sheath that covers nerve cells in the brain and spinal cord. Chronic ...

Duke Health researchers found a relationship between immune response and neurological behavior after studying mice with a specific gene mutation, which exhibited signs of ADHD in response to an ...