Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often ...

Periodontitis is characterized by the loss of teeth resulting from inflammation of gums due to bacterial infections. The susceptibility to such bone loss disorders increases with age. The expression ...

Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

The investigators closed their report by explaining that while therapies like tenapanor and SNF472 have shown promise, and ...