Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...

Cells have a clever way to transport cargos like growth factors across the cell membrane and into the cell. It is called clathrin-mediated endocytosis. Molecules of the protein clathrin gather on the ...

Wif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administering Wif1-overexpressing ...

Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

After it fills with cargo, the pit pinches off to form a clathrin-coated, membrane-bound vesicle inside the cell, which then proceeds to its proper destination. In cultured cells, hundreds of these ...