Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...

Spatial transcriptomics technologies can capture gene expression at spatial loci. However, at certain resolutions, the obtained gene expression reflects the sum of either a heterogeneous or ...

Recent advances in sequencing- and imaging-based techniques have led to the development of spatially resolved transcriptomics, named method of the year in 2020 1 with the ability to spatially quantify ...

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...

Spatial transcriptomics has emerged as a powerful tool for in situ analysis of gene expression within tissues. However, current technologies still face several challenges, including high costs, ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a ...

Transcriptomics is the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome at a specific time or under particular conditions. It involves the analysis of ...