Astrocytes are integral constituents of the central nervous system, serving roles that extend far beyond mere structural support. These specialised glial cells are crucial for maintaining homeostasis, ...

PET imaging of reactive astrocyte-neuron interaction reveals new insights into Alzheimer's disease pathology, offering a potential breakthrough in diagnosis and treatment Recently, a team of South ...

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

Researchers engineer CAR-astrocytes to target and remove amyloid plaques in Alzheimer’s, showing a 50% reduction in brain ...

Once overlooked, astrocytes are increasingly recognized as star players in Alzheimer’s disease, with recent studies blaming them for feeding into a neurotoxic stew that kills neurons. In the September ...

A single treatment of viral vector-delivered CAR-A construct in mice with existing plaque saturation cut the amount of amyloid plaques in half.

When the brain is injured in some way, a wide range of biochemical changes are triggered that can affect crucial brain cells known as astrocytes. They are a type of glial cell, and brain injuries ...

As neuronal supporters and immune surveyors, astrocytes and microglia are no mere bystanders to the neuronal mayhem that unfolds in Alzheimer’s disease. At the AD/PD meeting, held March 5-9 in Lisbon, ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

The selective MAOB inhibitor KDS2010 significantly improved functional recovery in a spinal cord injury animal model. Treated animals showed marked restoration of behavioral scores and locomotor ...