RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

Selecting an RNA-seq workflow requires more than matching a kit to a sample type. Choices around ribodepletion, strandedness, and unique molecular identifiers (UMIs) directly influence data quality ...

A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

While RNA sequencing (RNA-seq) has become a standard tool for profiling which genes are active in an organism, determining ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

Circular RNA (circRNA) is a unique type of non-coding RNA produced by back splicing of mRNA to form the covalent junction without 3’-5’ polarity and poly(A) tail. CircRNA was first discovered about 30 ...

SG-NEx provides an open-access resource for the global research community, accelerating biomarker discovery and precision medicine through: Singapore – A team of scientists led by the A*STAR Genome ...

LazySlide, a new computational tool designed to connect whole-slide pathology images with RNA sequencing data through ...

Researchers at Hiroshima University have developed a new tool to quickly and accurately map fungal gene functions, even for ...