A new single‑cell method, CIPHER‑seq, measures RNA and proteins together to reveal real‑time cytokine signaling.

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic ...

Understand the stages of a standard RNA-seq bioinformatics workflow, including the role of QC, alignment, gene expression quantification, and specialized application analyses Identify key QC metrics ...

A long-standing belief about HIV has quietly shaped how scientists think about the virus. For decades, researchers described ...

Marlene Belfort does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life, offering fresh insight into how a father’s age may influence the earliest stages of ...

The so-called ticking biological clock has been framed largely as a concern for women. We talk about egg freezing, ovarian reserve, and the ticking timeline of maternal fertility. Meanwhile, the male ...

Researchers led by Davide Incarnato at the University of Groningen have demonstrated that the FDA-approved cancer drug ...

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute ...