Post-translational modifications (PTMs) of tubulin, including acetylation, glutamylation and detyrosination, play a critical role in dictating the dynamic behaviour and specialised functions of ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and biomarker discovery in proteomics.

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Built on groundbreaking research from Israel ’s Weizmann Institute of Science, Promise Bio developed the first cloud-based platform for broad epiproteomics, helping researchers uncover disease ...

This multidisciplinary project integrates computational biology, structural modelling, population genomics, and AI. It will provide new mechanistic insights into how coding variation and PTMs ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

Explore how proteomics in biomarker discovery accelerates diagnostic assay development and improves clinical validation.

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Christine Dunham is a leading expert on the ribosome—an elaborate macro-molecular machine that operates like a factory within ...