Researchers have created a method called optovolution that uses light to guide the evolution of proteins with dynamic behaviors. By engineering yeast cells so their survival depended on proteins ...
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Light-guided ‘optovolution’ creates proteins that flip states on cue
A peer-reviewed study published in Cell in March 2026 introduces “optovolution,” an in vivo directed-evolution system that uses light to breed proteins capable of switching between active and inactive ...
EPFL researchers have developed a light-based method that can produce proteins that switch states, respond to signals, and even compute, using light and the cell cycle.
The world of protein engineering just took a giant leap forward. A team in China has developed a method that makes designing better proteins faster, cheaper, and easier. Led by Professor Gao Caixia ...
A research team led by Sahand Jamal Rahi at EPFL’s Laboratory of the Physics of Biological Systems has introduced a new ...
The key insight with a new strategy for training protein engineering models, called EvoRank, is to harness the natural variations of millions of proteins generated by evolution over deep time and ...
The Molecular Evolution, Protein Engineering, and Production (MEPEP) Facility, part of the Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), is a new discovery resource ...
A new platform combines rational protein design with continuous evolution to discover functional molecules more efficiently. In medicine and biotechnology, the ability to evolve proteins with new or ...
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