Loss and dysfunction of synapses have been linked to age-related cognitive decline and observed in Alzheimer's and other ...

Scientists now watch and reverse Alzheimer’s brain tangles via fluorescence anisotropy. The analytical tool uses chelators to ...

Using fluorescence anisotropy, researchers monitored how excess copper ions promote amyloid-beta aggregation. They identified chelators that selectively bind copper, pointing toward therapeutic ...

Scientists have identified a conserved aging-related protein, EPS8, that promotes toxic protein aggregation linked to neurodegenerative diseases.

Clearance mechanisms are key to removing aggregates and maintaining metastability.

The factor that tips you over the edge from being at risk for a disease to actually developing the disease is not always clear. Now, researchers from Japan report one factor that triggers problematic ...

Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

Researchers at the VIB-KU Leuven Center for Microbiology and the VIB-KU Leuven Center for Brain & Disease Research revealed a mechanism involving protein aggregation that allows bacteria to enter a ...

Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for ...

Yeast prions are increasingly recognised as pivotal agents in non-Mendelian inheritance, whereby protein conformations rather than nucleic acids dictate heritable traits. In Saccharomyces cerevisiae ...

The pathway leading to the telltale sign of ALS, protein aggregation in the cytoplasm of motor neurons, has been revealed. Researchers from the University of California – San Diego (CA, USA) have ...