The progression from a normal cell to a fully malignant cancer cell involves a number of steps that result in the selection for poorly regulated self-renewal, deregulated proliferation, successful ...

50 Years ago we suggested that cell death was ‘programmed’ or written into the developmental pattern of cells. Since that time we have come to understand the phenomenon of apoptosis, to understand its ...

Programmed cell death protein 1 (PD1) when coupled with its ligands programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2), functions as a ‘braking system’ within the immune system.

A landmark study by Indian researchers has not only found evidence of cells recovering from the near-death stage but has also found the molecular mechanism that drives the recovery process, the ...