Published in Current Molecular Pharmacology, a comprehensive review led by Yong Xu and colleagues from Shanghai Pulmonary Hospital explores the emerging role of lactylation, a post-translational ...

Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

Researchers have developed a method for studying an important, yet often overlooked, posttranslational modification.

One of the first things that students learn when they enter a biology class is the central dogma: DNA → messenger RNA → proteins. Only about 3% of the human genome directly codes for proteins, which ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...

Unlike bacteria or yeast, moss can produce large polypeptides of human collagen along with the post-translational modifications that make it stable and bioactive.

Integrating proteomics with systems biology reveals complex cellular networks, improving disease mechanisms understanding and precision medicine applications.

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular mutation that impairs a crucial enzyme's ability to help drive energy ...