Notch signalling is an evolutionarily conserved pathway that regulates cell fate decisions through direct cell–cell contacts. In the healthy central nervous system, it orchestrates neural stem cell ...
Myeloid lineage cells, such as monocytes, macrophages, dendritic cells (DCs), neutrophils, myeloid-derived suppressor cells, osteoclasts, or microglia, are important contributors to inflammatory and ...
Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...
Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...
Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...
Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
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