The American Journal of Managed Care

ESR1 Mutation Testing and Precision Medicine in Patients With ER+/HER2- Metastatic Breast Cancer

Experts discuss the necessity of ESR1 mutation testing when considering treatment with elacestrant in patients with estrogen receptor–positive (ER+)/HER2-negative (HER2–) metastatic breast cancer and ...
National Geographic news

Should you get tested for a BRCA gene mutation? It’s complicated.

Certain genetic mutations can boost your risk of breast cancer. Here’s what experts say you need to know when making the decision to get tested. Possible anomalies in a breast cancer screening are ...
Medscape

Blood-Based KRAS Testing Fails in Low-Grade Ovarian Cancer

Blood-based circulating tumor DNA (ctDNA) testing has proven to be insufficient for detecting KRAS mutations in patients with low-grade serous ovarian cancer (LGSOC), according to a study. The ...
The American Journal of Managed Care

HER2- Mutation Testing Considerations and Timing

Integrating HER2-directed therapies into NSCLC decision-making requires adapting protocols and ensuring timely updates as new therapies emerge. Streamlined processes and enhanced communication among ...
Business Insider

I got tested for the BRCA2 gene mutation after my mom was diagnosed with breast cancer. A simple test gave me peace of mind.

I was 18 when my mom was diagnosed with breast cancer. It altered the trajectory of my second year at college and changed how I viewed my mom, whom I naively thought was exempt from harm. She knew ...
Nature

Patient-centric thresholding of Cobas® EGFR mutation Test v2 for surveillance of EGFR-mutated metastatic non-small cell lung cancer

Circulating tumor (ctDNA) is increasingly used for cancer diagnosis and monitoring. ESMO and ASCO recognize the clinical utility of liquid biopsy for diagnostic purposes and to identify actionable ...
Kaleido Scope

Known Mutation Testing (KT2)

We offer targeted detection of a previously characterized mutation within the family. From a fresh EDTA blood sample, DNA is extracted directly and the target region is amplified and directly ...
Healthline

Muscular Dystrophy and Genetic Testing: Your Questions Answered

Genetic testing can confirm a muscular dystrophy (MD) diagnosis when symptoms and other tests already suggest MD. It also identifies specific gene mutations that can guide targeted treatment. Genetic ...
ascopubs.org

Podcast: Testing for ESR1 Mutations to Guide Therapy for HR-Positive, HER2-Negative Metastatic Breast Cancer Rapid Recommendation Update

Dr. Angie DeMichele and Dr. Lynn Henry present the latest rapid recommendation impacting two ASCO guidelines. This update focuses on testing for ESR1 mutations in patients with hormone ...
Business Insider

I got tested for the BRCA gene mutation while I was pregnant. With my family history, I knew I wanted a double mastectomy regardless of the results.

Eleven years after my mother died in 1994, when I was 31, I learned that a simple blood test could confirm whether I was a carrier of a BRCA gene mutation. Named for the first two letters of "breast" ...
Healthline

Navigating Cystic Fibrosis Testing in Pregnancy

Cystic fibrosis is an inherited illness that can be screened for during pregnancy. The test determines whether you have any altered genes that you can pass on to your child. Having the information can ...