A clustered family history of breast, ovarian, and colon cancers appropriately triggered germline testing, with BRCA1 mutation status informing individualized risk stratification and counseling.

Neurogeneticists have discovered a novel genetic mutation and associated buildup of toxic proteins in the brain -- a type of buildup distinct from amyloid or tau, proteins that have long been the ...

Beam is advancing BEAM-304 using an approach in which multiple mutation-specific base editors are developed within a single clinical program.

CHICAGO, Jan 8 (Reuters) - Scientists have characterized the role of thousands of mutations in the BRCA2 cancer gene, findings that may help reassure worried patients about their cancer risk or guide ...

Women with BRCA1/2 mutations are faced with complex decisions about breast and ovarian cancer risk management. This study was conducted to determine the effect of a tailored decision support system ...

An international team of scientists headed by researchers at the University of Edinburgh, has created a complete map showing how hundreds of possible mutations in a key cancer gene, CTNNB1, influence ...