Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.
Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...
Predicting which proteins bind to each other, or protein-protein interactions, has been a challenge for methods based in computational biology. One of the reasons is primarily due to the vast ...