There are three SAS procedures that enable you to do maximum likelihood estimation of parameters in an arbitrary model with a likelihood function that you define: PROC MODEL, PROC NLP, and PROC IML.

In this article the problem of obtaining the maximum likelihood estimates of the parameters from a special type of linear combination of discrete probability functions is discussed. It is shown that ...

The rapid accumulation of genome sequence data has made phylogenetics an indispensable tool to various branches of biology. However, it has also posed considerable statistical and computational ...