A new machine learning model built using a simple and interpretable approach predicts in-hospital death in patients with acute liver failure and reveals top risk drivers.
The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...
A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1 -- the most prevalent form of adult-onset muscular dystrophy -- provides insight into why patients develop fatty liver ...
Explore the serious implications of liver congestion and its connections to fibrosis, cirrhosis, and liver cancer in recent ...
The long-term stasis of blood in the liver, known as chronic liver congestion, can lead to a range of diseases, some of which ...
Periportal assembloid, with the three component cell types visualized: cholangiocytes in pink, portal fibroblasts in green, and hepatocyte nuclei in blue; all cell borders are visualized in white. New ...
Alcohol-associated liver disease (ALD) remains a leading cause of cirrhosis and liver-related mortality worldwide, with few effective therapies.
The paper S. Hoehme et al., “Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration,” PNAS, 107:10371-76, 2010. Free ...