An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...

Lipids are a diverse group of organic compounds that are essential for several biological functions, ranging from energy storage to cell signaling. They are loosely described as organic, ...

The discovery and mass production of life-saving therapeutics and vaccines is a lot more intricate than the initial synthesis. A compound can face various complications throughout the development and ...

Although lipid nanoparticles (LNPs) are the most advanced mRNA delivery carriers in clinical practice, further optimization is still ongoing. An ideal ionizable cationic lipid needs to meet three ...

The chemical industry applies lipid analysis and characterization in creating specialty chemicals and polymers. Lipids can serve as raw materials in polymer chemistry. For instance, lipid-based ...

In this article, data-dependent acquisition (DDA) experimental data collected by the ZenoTOF 8600 system was analyzed with MS-DIAL 5.5 software to detect and classify lipid molecular species in human ...