Spinocerebellar ataxia (SCA) is a group of autosomal dominant neurodegenerative disorders clinically showing adult-onset progressive cerebellar ataxia as a cardinal feature. 1 Extracerebellar signs, ...
In this week’s Neuron, researchers report that polyglutamine-expanded huntingtin (Htt)—the direct cause of Huntington's disease—exacerbates inositol triphosphate-mediated calcium signaling. The ...
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