The Ad26.COV2.S vaccine, which was approved as a single-shot immunization regimen, has been shown to be effective against severe coronavirus disease 2019. However, this vaccine induces lower severe ...

Assessing the immunogenicity, the ability of a foreign substance to elicit an immune response, of any drug or therapeutic is essential to assessing efficacy and toxicity at the early stages of drug ...

Early Removal of T-Cell Epitopes Reduces Risk of Adverse Immune Responses in Patients The development of therapeutic proteins such as humanized antibodies and fully human antibodies has in many ...

A new article in the journal Nucleic Acid Therapeutics addresses the recognition by the U.S. Food and Drug Administration that immunogenicity assays may be necessary to measure immune responses to ...

Group A meningococci are the source of major epidemics of meningitis in Africa. An affordable, highly immunogenic meningococcal A conjugate vaccine is needed. We conducted two studies in Africa to ...

Neoadjuvant durvalumab and tremelimumab in resectable locally advanced SCC of the oral cavity: DUTRELASCO study. Combined pulsed radiotherapy (QUAD shot regimen) with immune checkpoint inhibition (ICI ...

PROVIDENCE, R.I., April 1, 2024 /PRNewswire/ -- In the pursuit of developing novel biologic entities, scientists harnessing the power of AI and generative biology depend on computational tools for ...

Symposium brings together global leaders in immunogenicity to connect with China’s rapidly evolving pharmaceutical development landscape Speakers include thought leaders in biotherapeutics, complex ...

Corticosteroids are known to diminish immune response ability, which is generally used in routine premedication for chemotherapy. The intersecting of timeframe between the corticosteroid's duration of ...