Organoid models of the small intestines are now a closer match to the cellular architecture of the human intestine, thanks to the work done by the Organoid group at Hubrecht Institute in the ...

To better understand our organs and perform tests on a more human-like proxy, researchers are increasingly turning to organoids: miniaturized tissue cultures, usually in the form of organs, that are ...

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine. This will help them to better study the ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

The human gastrointestinal tract is in a constant state of flux; it hosts a diverse and dynamic community of microbes known as the gut microbiome, and is constantly exposed to things in the ...

The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the ...

Organ-Chips as a Platform for Studying Effects of Space on Human Enteric Physiology (Gut on Chip) examines the effect of microgravity and other space-related stress factors on biotechnology company ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...