Nature

The role of HLA antibodies in allogeneic SCT: is the ‘type-and-screen’ strategy necessary not only for blood type but also for HLA?

Although several early studies on HLA haploidentical-SCT in the 1980s implicated a role of HLA antibodies in graft failure, 6, 7 it has been generally recognized to have a minor role in graft failure ...
Nature

Effective desensitization of donor-specific HLA antibodies using platelet transfusion bearing targeted HLA in a case of HLA-mismatched allogeneic stem cell transplantation

The patient was a 41-year-old Japanese female who had been diagnosed with breast cancer, and chemotherapy for breast cancer-related AML. She underwent allogeneic HSCT using cord blood units, but AML ...