The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then ...

“BORT” (pictured) IS ONE OF THE OLDEST MALE ROTTWEILERS LIVING IN NORTH AMERICA THAT INVESTIGATORS PUT TO WORK TO DISCOVER THE LINKAGE BETWEEN LIFELONG GONAD FUNCTION, LATE-LIFE FRAILTY, AND OVERALL ...

A new study examined gonad function in male SLE patients and found that they have a high frequency of sperm abnormalities associated with reduced testicular volume. The prognosis for systemic lupus ...

A preliminary study by a Wuhan medical team found the first clinical evidence the novel coronavirus (COVID-19) infection could harm male gonad functions by significantly increasing sex hormones.

Short stature and gonad failure can be a severe side effect of the conditioning protocol used before hematopoietic cell transplantation (HCT). The final height after HCT is not reduced in patients ...

Panel A shows the internal structures of a 46,XY patient with pure gonadal dysgenesis. There are bilateral streak gonads with retained müllerian structures, fallopian tubes, and a midline uterus.

The gonad arises as a bipotential organ primordium. Expression of the Y-linked gene, Sry, in the bipotential gonad leads to the differentiation of Sertoli cells, which orchestrate testis development.