Researchers found a commercial deworming tablet released only 10% of its drug content in dissolution testing, prompting investigation of new formulations designed to improve drug release and extend ...
When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your bloodstream to provide benefits over the specified period of time. When the drug ...
Drug delivery as solid dosage forms is complex with a number of factors that can noticeably influence their therapeutic benefit. The drug must be stabilized in the tablet and at the same time be ...
Over 141,000 bottles of cholesterol medication have been recalled due to “failed dissolution specifications,” suggesting that the drugs did not pass a solubility test, or failed to dissolve at a ...
What is the process of oral drug absorption, and how has the Fa equation evolved? Oral drug absorption begins with administering a drug product, followed by a rapid disintegration process. The drug ...
Teva issued a voluntary recall for two lots of its hypertension drug Matzim LA (diltiazem hydrochloride) after testing found the extended-release tablets failed to dissolve correctly. The recalled ...
Engineers filled a glass tube bent like a tuning fork, kept vibrating by a circuit at its resonance frequency, with simulated stomach and intestine contents and passed an over-the-counter time-release ...
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Understanding Particle Drift and its Influence on Oral Drug Absorption Using Flux Tools
In this interview, Karl Box from Pion outlines the benefits of particle drift analysis using flux tools and how this can be used to enhance oral drug absorption in pharmaceutical research. Pion's ...
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