Rodent ClC-K1 and ClC-K2, and their respective human orthologs ClCKA and ClCKB, are chloride channels specific to the kidney (and inner ear); Barttin is their functionally important subunit. ClC-K1 is ...
Hypertension affects 1 billion people world-wide, contributing to 5 million deaths annually from myocardial infarction, stroke, kidney failure and heart failure. Its causes have been obscure owing to ...
The kidney carries out important functions via microscopic functional units called nephrons. Researchers are investigating which factors control the formation and function of specific segments of the ...
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