This allowed them to pinpoint where in the cell sheet extrusion would occur. These discoveries provide a significant step forward in our understanding of how the physical microenvironment plays a role ...
Figure 2: MDCK WT epithelia behave as 2D, extensile, active nematic liquid crystals. Figure 3: Compressive stresses at +1/2 defects trigger both cell extrusion and YAP mechanosensitive response and ...