Restriction mapping is a method used to map an unknown segment of DNA by breaking it into pieces and then identifying the locations of the breakpoints. This method relies upon the use of proteins ...
Optical mapping is a powerful genetic identification tool that so far has been limited to lower organisms. Now a USC-led team of computational biologists has made the method practical for human ...
A long-range optical DNA mapping technique has proved its worth in a clinical setting, successfully identifying large structural variants in DMD, the gene responsible for Duchenne muscular dystrophy.
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