A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...

The discovery suggests that the protein may influence both brain diseases and cancer, potentially reshaping how scientists think about these major health conditions.

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

A protein, TDP43, previously linked to dementia and ALS, has been found to control DNA repair. Researchers say abnormal ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression. Research has identified a critical DNA repair ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...