Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

A new microfluidic chip simplifies detecting and quantifying DNA by analyzing electrical impedance signals that vary based on DNA flowing across a biosensor inside the chip. The proof-of-concept ...

DNA's 3D shape — its twisted ladders complexly curled into coils and loops — and other features beyond its genetic code may influence where "hotspots" of cancer-causing mutations accumulate. That's ...

Proteins are like Spider-Man in the multiverse. The underlying story is the same: each building block of a protein is based on a three-letter DNA code. However, change one letter, and the same protein ...

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. UCLA researchers, using an experiment that elucidated the function of tens of thousands of ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...