The threat of DPC lesions Every time a cell divides into two, it must accurately create a copy of all its DNA, a process that involves the tight coordination of sophisticated molecular machinery.
An artificial intelligence-predicted image of a region in the SPRTN enzyme (green structure) that can recognise and bind to ubiquitin chains (orange structure). Researchers at the University of Oxford ...
Morning Overview on MSN
Study links an ALS-related protein to DNA repair, cancer, and dementia risk
A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...
Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from embryonal ...
DNA-protein crosslinks (DPCs) are bulky lesions in which unwanted proteins attach to DNA, blocking the process of copying the cell's DNA. If left unrepaired, DPCs can cause neurodegeneration, ...
(a) Schematic representation of study design, experimental and computational processing including host filtration using the Human Pangenome Reference Consortium, microbial classification using Qiita ...
Professor Chao Zhang’s team at Zhujiang Hospital, Southern Medical University, has developed a novel DNA nanomachine–based drug delivery and release ...
A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer ...
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