Leptin is a neurotransmitter that is produced in fat cells and is involved in appetite. Leptin works through the action of several small proteins called neuropeptides, such as thyrotopin-releasing ...

Thirty years after its discovery, scientists are eyeing leptin with renewed interest, for everything from weight loss drug ...

Research on young mice into leptin has suggested that the hormone can change their brains’ circuitry, creating permanent controls on their appetite, henceforth controlling obesity. According to a ...

Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, Yale School of Medicine researchers have found that the hormone also ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...

Obesity is often a combination of genetic and lifestyle factors. Genetics can influence metabolic pathways, appetite control, and energy storage. Leptin resistance can lead to increased appetite and ...

Those little fruit flies floating around the ripening cantaloupes pack some fat between their tiny wings. They’re cold-blooded and burn their fat to warm up. “They have really beautiful fat, the flies ...