For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...
Tumor biology is increasingly recognized as a field shaped by the intricate interplay between malignant cells and their surrounding microenvironment. Recent ...
Omics-driven insights into tumor microenvironment determinants of immunotherapy response in melanoma
Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...
The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...
How tumor microbes shape cancer: New insights into microbial diversity in the tumor microenvironment
Intratumoral microbiota—the microbial populations residing within solid tumors—have emerged as pivotal components of the tumor microenvironment (TME), influencing tumor initiation, progression, and ...
Among the presentations included in the Top Abstracts category at the recently inaugurated Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, it is worth highlighting ...
In this piece, I highlight one particular talk that caught my interest — given by Elana Fertig, Dean E. Albert Reece Endowed ...
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Study reveals cellular and metabolic landscape of lymph node metastasis in breast cancer
A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast ...
A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...
A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...
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