Traditionally, scientists have used 2D cell cultures as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Learn how animal-free 3D systems can reduce variability in drug discovery, leading to better human biology representation.

Live-cell analysis and stem cell isolation techniques help researchers fully leverage 3D spheroid models, bridging the gap between in vitro findings and in vivo outcomes. When derived from isolated ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences ...

3D-printed lungs made with living cells could help to improve lung disease prevention and treatment—and potentially one day offer a lab-grown option for use in organ transplants. University of ...

Researchers have shown that activation of the protein YAP, known to help cancer cells survive treatment, behaves very differently in cell culture models depending on how they are grown in the lab, ...

One way cancer specialists detect the disease is by examining cells and bodily fluids under a microscope, a time-consuming ...

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...